Fructose Malabsorption in Northern Norway
Phase 2
Completed
- Conditions
- Fructose MalabsorptionIrritable Bowel Syndrome
- Interventions
- Behavioral: diet restriction
- Registration Number
- NCT00555191
- Lead Sponsor
- University Hospital of North Norway
- Brief Summary
Different published studies has shown a possible co-variation between leakage of fructose to the great bowel and exacerbation of irritable bowel syndrome (IBS) symptoms.
The aim of the FINN trial is to study the role of fructose malabsorption in patients with IBS in order to evaluate different diagnostic criteria for fructose malabsorption and at the same time study the effect of diet treatment in this cohort of patients and estimate the prevalence of fructose malabsorption.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 182
Inclusion Criteria
- IBS patients satisfying ROME 2 diagnostic criteria
Exclusion Criteria
- Seriously ill
- Organic abdominal disease
- Other functional bowel disease
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description 1 diet restriction PATIENTS IN THIS ARM IS INSTRUCTED IN FRUCTOSE REDUCED DIET FOR A PERIOD OF 3 MONTHS
- Primary Outcome Measures
Name Time Method VAS score og specific abdominal complaints.SGA score of relief related to abdominal complaints. 12 weeks
- Secondary Outcome Measures
Name Time Method Estimate sensitivity,specificity,negative and positive predictive value using 50 gm fructose in breath test.Validate questionary for intolerance.Validate VAS in judging changes in abdominal complaint.Examine polymorphism i Glut5 transporter gene. 12 weeks
Trial Locations
- Locations (1)
Hospital of Rana Medical Dep. Helgelandsykehuset HF
🇳🇴Mo i Rana, Nordland, Norway