Fructose malabsorption and serotonin-associated psychological symptoms in children and adolescents
- Conditions
- Fructose malabsorption and accompanying serotonin-associated psychological symptoms
- Registration Number
- DRKS00031047
- Lead Sponsor
- Institut für Psychologie, Goethe-Universität Frankfurt
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 55
Inclusion Criteria
Study group 1: Fructose malabsorption
Study group 2: Combination of fructose and lactose malabsorption
Exclusion Criteria
Control sample: Exclusion of intestinal fructose malabsorption and exclusion of a combination of fructose and lactose malabsorption
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The present study is based on the consideration that children and adolescents with an untreated fructose malabsorption may suffer from concomitant psychological symptoms, which are associated with a reduced intestinal absorption of tryptophan and therefore dysregulated processes of the serotonergic system. More precisely, it is hypothesized that children and adolescents with fructose malabsorption more likely show heightened serotonin-associated psychological symptoms (scales anxiety, depression and obsessive-compulsive disorder/tic of a screening questionnaire) than externalizing ones (attention-deficit/hyperactivity disorders and oppositional defiant and conduct disorders of the screening questionnaire). Additionally, it is hypothesized that fructose-malabsorbers would show higher levels of serotonin-associated internalizing psychological symptoms than a healthy control group.
- Secondary Outcome Measures
Name Time Method Furthermore, the degree of symptom expression is assumed to be related to eating behavior. It is expected, that within the group of children and adolescents with fructose malabsorption, the quantity of fruit sugar consumption would correlate with the degree of serotonin-related psychological symptoms.