Outcomes of Critically Ill Patients With Severe Acute Kidney Injury Requiring Renal Replacement Therapy

Completed

• Conditions: Critical Illness; Acute Kidney Injury

• Registration Number: NCT02897310
• Lead Sponsor: University Hospital, Brest

Brief Summary

This study assess the vital status, renal function and renal recovery of patients admitted to intensive care unit and requiring renal replacement therapy for acute kidney failure. Patient follow up is up to 3 years after ICU admission when possible.

Detailed Description

Up to 50% of critically ill patients develop acute kidney injury and up to 10% require renal replacement therapy in the intensive care unit. This study aims to identify factors associated with mortality and to evaluate renal recovery of patients who had acute kidney failure requiring renal replacement therapy in intensive care unit at 1 and 3 years post intensive care unit admission.

Study Timeline

• Study Start: 2014-11
• Primary Completion: 2015-05
• Study Completion: 2015-05
• Study First Submitted: 2016-08-19
• Status Verified: 2016-09
• Study First Submitted QC: 2016-09-07
• Last Update Submitted: 2016-09-07
• Study First Posted: 2016-09-13
• Last Update Posted: 2016-09-13

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 245

Inclusion Criteria

• Adults admitted to the intensive care
• Acute kidney failure requiring renal replacement therapy

Exclusion Criteria

• Patients suffering end stage renal failure requiring chronic renal replacement therapy
• Patients under 18 years

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
one-year mortality	year 1	vital status

Secondary Outcome Measures

Name	Time	Method
hospital mortality	year 1
one year renal function	Year one

Trial Locations

Locations (1)

CHRU de Brest; 🇫🇷 Brest, France