MedPath

eurochemische Modulation von Exekutiv- und Gedächtnisfunktione

Conditions
Progressive cognitive decline in physiological aging
Registration Number
EUCTR2005-000434-21-DE
Lead Sponsor
Kognitive Neurologie, Institut für Medizin, Forschungszentrum Jülich
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Authorised-recruitment may be ongoing or finished
Sex
All
Target Recruitment
Not specified
Inclusion Criteria

-Healthy subjects age range 18-75 years
-Right-handed
-fluent in German language
-capable of informed consent
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

-neurological or psychiatric disease
-any severe medical condition
-asthma bronchiale, suspicion of melanoma, gangrene, coronary heart disease, mechanical
obstipation of bowels or urinary pathways, glaucoma, hyperthyreosis, cardial arrhythmia, diarrhea
-known allergic reactions to Sulfite, Glycopyrroniumbromid, Levodopa/Carbidopa,
Physostigminsalicylate
-regular intake of centrally active pharmacological agents
-intake of MAO-A-inhibitors or other cholinesterase-inhibitors
-pregnancy or lactation
-incorporated ferromagnetic objects (e.g. pace-maker, intrauterine-devices, endoprothesis of the joints, tattoos, etc.)

Study & Design

Study Type
Interventional clinical trial of medicinal product
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
© Copyright 2025. All Rights Reserved by MedPath