The Effect of Probiotics on Exacerbation of Inflammatory Bowel Disease Exacerbation (Crohn's Disease)
- Registration Number
- NCT01765998
- Lead Sponsor
- The Baruch Padeh Medical Center, Poriya
- Brief Summary
Inflammatory Bowel Disease (IBD) is an immune mediated chronic intestinal condition. It includes ulcerative colitis (UC) and Crohn's disease(CD). probiotics have been shown to be effective in varried clinical conditions ranging fron infantile diarrhea, necrotizing enterocolitis,helicobacter pylori infections, etc.
- Detailed Description
This is a prospective study that will enroll 50 patients with Crohn's disease.Each patient will get the study medication for 6 weeks and will be evaluated twice- before enrollment and after 6 weeks of treatment.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
- patients with Crohns' disease who are stable or have mild acute exacerbations that do not necessitate treatment with systemic corticosteroids
Exclusion Criteria
- pregnant women, under 18 years or over 60 years,
- patients with known ulcerative colitis,
- patients with any cancer,
- patients with heart failure
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description placebo Placebo This will be the comparison group to the experimantal group that recives Probiotic. Probiotic Probiotic To study the effect of probiotic on the ability to build endothelial progenitor stem cells and to study clinical recovery of patients with Crohn's Disease.
- Primary Outcome Measures
Name Time Method endothelial stem cells one year to study the ability to create endothelial progenitor stem cells following probiotic management compared to placebo group
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Baruch Padeh Medical Center
🇮🇱Tiberias, Lower galilee, Israel