Inflammation and Coagulation Factors for Predicting Cerebral Edema After SAH
Recruiting
- Conditions
- Coagulation and Hemorrhagic DisordersInflammationCerebral Edema
- Registration Number
- NCT06009016
- Lead Sponsor
- Second Affiliated Hospital, School of Medicine, Zhejiang University
- Brief Summary
Explore the role of Inflammation and coagulation factors in cerebrospinal fluid for predicting persistent cerebral edema after subarachnoid hemorrhage
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
- Subarachnoid hemorrhage patients admitted to our neurosurgery department with modified Fisher Scale 3-4, with a confirmed radiographic diagnosis.
Exclusion Criteria
- Angiogram-negative patients, patients with a history of trauma or previous brain injury (stroke, hemorrhage, surgery et al. which left associated chronic changes on CT), arteriovenous malformation, radiological data lost, accompany with serious comorbidities before subarachnoid hemorrhage onset (such as coagulation defects, uncontrollable hypertension, and arrhythmia et.al.), initial radiological data performed more than 3 days after SAH onset
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Cerebral edema after subarachnoid hemorrhage At 3 and 7days after SAH onset Cerebral edema after subarachnoid hemorrhage will be determined by the SEBES score. SEBES 0-2 is mild edema; SEBES 3-4 is severe edema.
Outcome at 3 months after subarachnoid hemorrhage 3 months after subarachnoid hemorrhage Outcome will be determined by the modified Rankin Score (mRS). mRS 0-2 is favorable outcome; mRS3-5 is poor outcome.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Second affiliated hospital of Zhejiang University, School of Medicine
🇨🇳Hangzhou, Zhejiang, China