NCT02984358已完成不适用
Effect of Chronic Mycoprotein Consumption, and of Its Nucleotide Content, in Uric Acid Concentrations and Other Markers of Metabolic Health in Adults
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 主要终点
- Serum uric acid concentrations
研究概览
简要总结
Compare chronic (one week) of a 'normal' meat diet with one week of mycoprotein consumption, with or without a reduced nucleotide content, on markers of metabolic health, such as uric acid concentrations, blood glucose control and blood lipid profiles.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •BMI between 18 and 30
排除标准
- •On medication (except contraception)
- •Diagnosed with any metabolic or cardiovascular conditions
- •BMI < 18 or > 30
- •Dietary restrictions (vegetarians/vegans, etc.)
结局指标
主要结局
Serum uric acid concentrations
时间窗: Measured at baseline; days 2, 4 and 6 of the intervention; and after the 1 week intervention (day 8)
次要结局
- Glycaemia and serum insulin - insulin sensitivity (oral glucose tolerance test)(Measured at baseline and after 1 week intervention (day 8))
- IL-6(Measured at baseline and after 1 week intervention (day 8))
- 24 h blood glucose homeostasis - measured using a Dexcom CGMS(Measured 5 days at baseline (habitual data) and 5 days during the intervention (days 3 - 7))
- Metabolomics (using Nuclear Magnetic Resonance - NMR)(Measured at baseline; days 2, 4 and 6 of the intervention; and after the 1 week intervention (day 8))
研究者
相似试验
已完成
不适用
Appetite Regulation and MycoproteinAppetiteEnergy IntakeNCT02053025Imperial College London52
已完成
不适用
Tolerance of Regular Meal Intake With Mycoprotein (TOMMY)Gastrointestinal ComplicationNCT04590768Wageningen University and Research24
已完成
不适用
Does the Ingestion of Mycoprotein Elicit an Optimal Anabolic Response in Resting and Exercised Skeletal Muscle?HealthyNCT02984345University of Exeter20
已完成
不适用
Tolerance of regular meal intake with mycoproteiNL-OMON50091Bioscienz24
尚未招募
不适用
TRIRES2HealthyHealthy VolunteersRPCEC00000403Genomic Biotechnology Center – National Polytechnic Institute (IPN-Reynosa), Mexico28