Does the Ingestion of Mycoprotein Elicit an Optimal Anabolic Response in Resting and Exercised Skeletal Muscle?

Not Applicable

• Conditions: Healthy
• Interventions: Other: Milk protein beverage; Other: Mycoprotein beverage

• Registration Number: NCT02984345
• Lead Sponsor: University of Exeter

Brief Summary

The present study will seek to quantify the muscle protein synthetic response to mycoprotein feeding, comparing it to milk protein as a gold standard and heavily researched positive control

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2016-12-02
• Study First Submitted QC: 2016-12-02
• Study First Posted: 2016-12-06
• Study Start: 2017-01-26
• Primary Completion: 2018-05-01
• Status Verified: 2021-05
• Last Update Submitted: 2021-05-25
• Last Update Posted: 2021-05-26
• Study Completion: 2022-05

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Male
• Target Recruitment: 20

Inclusion Criteria

• BMI between 18 and 30 -

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Exclusion Criteria

• Any diagnosed metabolic impairment (e.g. type 1 or 2 Diabetes)
• Any diagnosed cardiovascular disease or hypertension.
• Elevated blood pressure at the time of screening (e.g. blood pressure of ≥140/90mmHg).
• Chronic use of any prescribed or over the counter pharmaceuticals.
• A personal or family history of epilepsy, seizures or schizophrenia.
• Anyone with previous motor disorders.
• An allergy to mycoprotein / Quorn, penicillin, or milk.

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Milk protein beverage	Milk protein beverage	-
Mycoprotein beverage	Mycoprotein beverage	-

Primary Outcome Measures

Name	Time	Method
Muscle fractional synthetic rate (muscle protein synthesis)	7.5 hours

Secondary Outcome Measures

Name	Time	Method
Plasma amino acid concentration	7.5 hours
Serum insulin concentration	7.5 hours
Molecular markers of muscle anabolism	7.5 hours

Trial Locations

Locations (1)

University of Exeter, Sports & Health Sciences, College of Life & Environmental Sciences; 🇬🇧 Exeter, Devon, United Kingdom