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Clinical Trials/NCT04084652
NCT04084652
Completed
Not Applicable

Comparing the Muscle Protein Synthetic Response to Ingestion of Mycoprotein vs Protein Isolated From Mycoprotein

University of Exeter1 site in 1 country24 target enrollmentApril 15, 2019

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Anabolic Response to Mycoprotein and Micronutrient Ingeston
Sponsor
University of Exeter
Enrollment
24
Locations
1
Primary Endpoint
Muscle protein synthesis
Status
Completed
Last Updated
3 years ago

Overview

Brief Summary

Dietary protein is vital for the preservation of health and optimal adaptation to training. However, traditional animal proteins come with a number of economic, environmental, and ethical issues. Accordingly, there is a need to develop an understanding of the utility of more sustainable non-animal derived dietary proteins to support our nutrition. Mycoprotein, produced by Quorn Foods™, has recently been shown to stimulate a greater anabolic response within skeletal muscle compared with milk protein, suggesting its utility within sports nutrition. However, it is unclear what accounted for the greater anabolic response of mycoprotein. One explanation could be the non-protein nutrients contained within mycoprotein (e.g. fibre, carbohydrate, fat or micronutrients).

Therefore, the present study will compare the muscle anabolic response between mycoprotein (MYC) as a whole food and the protein isolated from mycoprotein (PIM).

Registry
clinicaltrials.gov
Start Date
April 15, 2019
End Date
December 11, 2019
Last Updated
3 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Male

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • BMI between 18 and
  • Resistance trained

Exclusion Criteria

  • Any metabolic impairments.
  • Cardio/pulmonary diseases.
  • Chronic use of over the counter pharmaceuticals
  • A personal or family history of epilepsy, seizures or schizophrenia.
  • Allergic to mycoprotein/Quorn/edible fungi/environmental mould products.

Outcomes

Primary Outcomes

Muscle protein synthesis

Time Frame: 7.5 hours

The rate of synthesis of new muscle protein (Fractional Synthetic Rate %/h)

Secondary Outcomes

  • Serum Insulin(7.5 hours)
  • Blood Glucose(7.5 hours)
  • Plasma Amino Acid Kinetics(7.5 hours)

Study Sites (1)

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