Pre-operative study the efficacy of nebulized Dexmedetomidine on blunting hemodynamic changes during intubation and pneumoperitoneum in morbid obese patients during laparoscopic bariatric surgery. Randomized double blind control study
Not Applicable
- Conditions
- Anaesthesia
- Registration Number
- PACTR202308566462034
- Lead Sponsor
- sherif kamal hafez arafa
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 90
Inclusion Criteria
1-This study will include 90 adult morbidly obese patients of both sex
2- with BMI (30-45),
3-ASA II-III physical status,
4-aged between 20-60 years
5- scheduled for elective laparoscopic bariatric surgery under general anesthesia.
Exclusion Criteria
1-Patients' refusal
2-Decompansated hepatic or renal or cardiac disease
3-Expected difficult airway management
4-Uncontrolled hypertension
5-Psychiatric disease
6-Sever pulmonary disease
7-Patient om opioid, alcohol, beta0 blockers or allergy to any of the study drugs.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary outcome is hemodynamic response to intubation and pneumoperitoneum.
- Secondary Outcome Measures
Name Time Method -Preoperative sedation score<br>-Intraoperative fentanyl consumption and propofol consumption for induction.<br>-Time for first use of rescue analgesia postoperatively.<br>-Total opioid consumption in the first 24 hours postoperative.<br>-Any adverse effects as cough, bradycardia and hypotension.<br><br>