The effect of pre-operative administration of Dexmedetomidine on pulse rate and blood pressure following the administration of Ketamine for electroconvulsive therapy

Phase 3

• Conditions: Condition 1: Blood pressure. Condition 2: Heart rate.; Elevated blood-pressure reading, without diagnosis of hypertension; Tachycardia, unspecified; R03.0; R00.0

• Registration Number: IRCT20160307026950N10
• Lead Sponsor: Esfahan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 21 May 2019

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 64

Inclusion Criteria

Patients candidate receiving electroconvulsive therapy
Patients older than 6 yeras old and younger than 25 years old
Patients with American society of anesthesiology physical status class 1,2 (ASAI,II)

Exclusion Criteria

Addiction to drugs and alcohol
History of cardio-pulmonary diseases
History of consumption of Beta blockers and narcotics and high blood pressure drugs
Drug allergy

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Heart rate changes. Timepoint: Before the intervention, 1 , 5, 10 minutes after end of seizure and then the discharge time of recovery. Method of measurement: Heart monitoring.;Mean arterial blood pressure. Timepoint: Before the intervention, 1 , 5, 10 minutes after end of seizure and then the discharge time of recovery. Method of measurement: Non invasive blood pressure monitor.;Duration of seizure. Timepoint: After intervention. Method of measurement: In seconds using a chornometer.;Oxygen saturation. Timepoint: Before the intervention, 1,5,10 minutes after end of seizure and then the discharge time of recovery. Method of measurement: Percent with pulse oximeter.;Recovery time. Timepoint: From the end of seizure to full consciousness. Method of measurement: Minute with using a chronometer.

Secondary Outcome Measures

Name	Time	Method
ausea and Vomiting. Timepoint: After end of the siezure. Method of measurement: Questionnaire.;Laryngospasm. Timepoint: After end of the siezure. Method of measurement: Evaluation of respiration and oxygen saturation.