Incidence, Characteristics and Outcome of Patients With New Diabetes Mellitus and Pre-Diabetes With First-time Diagnosed Coronary Artery Disease
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- PreDiabetes
- Sponsor
- Saud Al Babtain Cardiac Center
- Enrollment
- 300
- Locations
- 1
- Primary Endpoint
- Incidence
- Status
- Completed
- Last Updated
- 3 years ago
Overview
Brief Summary
A prospective analytic study to evaluate the incidence, clinical and laboratory characteristics, extent of coronary artery disease and short-term outcome of newly diagnosed diabetes and pre-diabetes in patients with first-time diagnosed coronary artery disease treated in Saud Al Babtain Cardiac Center.
Investigators
Eligibility Criteria
Inclusion Criteria
- •First time diagnosed coronary artery disease as confirmed by invasive coronary angiography
- •Emergently or electively admitted as coronary artery disease patients.
- •Informed consent form
Exclusion Criteria
- •Prior diagnosis of diabetes or pre-diabetes based on the diagnostic criteria of the American Diabetes Association (ADA, 2020)
- •Known coronary artery disease
Outcomes
Primary Outcomes
Incidence
Time Frame: Through study completion, an average of 2 year
The incidence, number and percent, of newly diagnosed diabetes and pre-diabetes in patients with first-time diagnosed coronary artery disease
Characteristics, clinical and laboratory
Time Frame: Through study completion, an average of 2 year
Clinical and laboratory characteristics of newly diagnosed diabetes and pre-diabetes in Patients with first-time diagnosed coronary artery disease.
Coronary artery disease severity
Time Frame: Through study completion, an average of 2 year
Extent of newly diagnosed coronary artery disease in newly diagnosed diabetes and pre-diabetes. The severity of coronary artery disease will be assessed using the SYNTAX score.
Short-term outcome
Time Frame: From admission to 1-month follow up.
Assessment will include in-hospital and 1-month major adverse cardiac events (MACE), recurrent angina, stent thrombosis, need for emergent/urgent coronary intervention, clinical heart failure and left ventricular dysfunction.