Comparison of the effects of Pregabalin, Dexmedetomidine, and their combination on the haemodynamic response and anaesthetic requirements

Not Applicable

Completed

• Conditions: ASA Grade 1 and 2

• Registration Number: CTRI/2017/09/009862
• Lead Sponsor: VMMC and Safdarjung Hospital

Brief Summary

arterial pressures  and anaesthetic requirements were significantly lower in the dexmedetomidine group in the perioperative period as compared to the other two groups.

Detailed Description

Not available

Study Timeline

• Study Start: 2012-05-11
• Study Completion: 2014-01-24
• Last Update Posted: 2017-09-18

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

• Patients scheduled to undergo elective laparoscopic cholecystectomy.
• ASA grades 1 and 2.
• Adult patients 18-65 years of age of either sex.

Exclusion Criteria

1. patients with hypertension,morbid obesity, and cardiac, renal, hepatic, endocrine or pulmonary dysfunction 2) ASA grades 3 and 4.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
pulse,blood pressure,oxygen saturation,end tidal carbon dioxide, isoflurane concentration,fentanyl requirement, propofol requirement, ramsay sedation score, Visual Analogue Scale	baseline, 10, 20,30,40,45,50,55,60 minutes after premedication | before induction, after 1,2,3 minutes of induction, after 1,3,5,10,15,30,45,60,75 minutes of intubation, before, after and end of pneumoperitoneum | 15 minutes, 1 hour, 2 hours after extubation

Secondary Outcome Measures

Name	Time	Method
time taken for patient to respond after reversal, time taken for extubation after reversal	15 minutes, 60 minutes, and 120 minutes postoperatively

Trial Locations

Locations (1)

SAFDARJUNG HOSPITAL; 🇮🇳 Delhi, DELHI, India

SAFDARJUNG HOSPITAL

🇮🇳Delhi, DELHI, India

Naveen K V

Principal investigator

8826773497

naveenkvijayan@gmail.com