Effect of Mineralocorticoid on Brown Fat in Humans with Primary Aldosteronism who will be treated with Surgery

Not Applicable

• Conditions: Primary aldosteronism; Obesity; Diet and Nutrition - Obesity; Metabolic and Endocrine - Other metabolic disorders

• Registration Number: ACTRN12614001129673
• Lead Sponsor: Professor Ken Ho

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-10-23
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 12

Inclusion Criteria

subjects with newly diagnosed primary aldosteronism who will be treated with surgery

Exclusion Criteria

Pregnancy

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Brown Fat volume changes on 18FDG-PET-CT scan[before and at least 4 weeks after surgery (but no more than 8 weeks after surgery)];Brown Fat activity changes on 18FDG-PET-CT scam[before and at least 4 weeks after surgery (but no more than 8 weeks after surgery)]

Secondary Outcome Measures

Name	Time	Method
Changes in resting energy expenditure assessed by indirect calorimetry[before and at least 4 weeks after surgery (but no more than 8 weeks after surgery)];Changes in diet-induced thermogenesis assessed by indirect calorimetry[before and at least 4 weeks after surgery (but no more than 8 weeks after surgery)]