Does statin therapy reduce sympathoexcitation in hypertensio

• Conditions: sympatisch zenuwstelsel, cardiovasculair (hypertensie); increased stress-sensitivenervous system activity; Sympathoexcitation

• Registration Number: NL-OMON30664
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 13 May 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 13

Inclusion Criteria

- Age 18-70 years
- Body mass index 18-35 kg/m2
- hypertension (see protocol)

Exclusion Criteria

- renal disease
- recent MI/CVA
- diabete
- diseases of the autonomic nervous system
- any other severe medical condition on the basis of the medical history and a careful physical examination before the study.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Muscle sympathetic nerve activity (MSNA), HRV, plasma norepinephrine levels, </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>blood pressure and cholesterol levels</p><br>