The Effect of Nutrition and BMI on on Lung Capacity, Functional Capacity and Mortality in End-Stage Lung Patients

Active, not recruiting

• Conditions: Lung Transplant
• Interventions: Procedure: Lung transplantation

• Registration Number: NCT06283680
• Lead Sponsor: Aylin Seylam Küşümler

Brief Summary

The aim of this study was to investigate the effect of nutritional risk index, BMI and body fat, muscle ratio on functional capacity, lung capacity, exercise capacity index, all-cause mortality, post-transplant intensive care unit stay and survival time in end-stage lung patients on the lung transplant list.

Detailed Description

This study aimed to determine the nutritional status of patients awaiting lung transplantation and examine the effects of nutritional status, immunonutrition use, and BMI on lung capacity, mortality, and health status after lung transplantation. The study was designed in two different periods. The first period was a retrospective descriptive study. During this study, we will examine the retrospective nutritional status of patients who are waiting for lung transplantation, those who exited while on the list, or those who have received lung transplantation. In the second phase, we will conduct face-to-face interviews with patients on the lung transplant list, take bioelectrical impedance analyses (BIA), and record 24-hour food consumption to examine their detailed nutritional status.

Study Timeline

• Study Start: 2023-02-28
• Study First Submitted: 2024-02-21
• Study First Submitted QC: 2024-02-21
• Study First Posted: 2024-02-28
• Status Verified: 2024-04
• Last Update Submitted: 2024-04-05
• Last Update Posted: 2024-04-08
• Primary Completion: 2024-04-28
• Study Completion: 2024-05-31

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 213

Inclusion Criteria

1. End-stage lung disease
2. To be on the Lung Transplant list.
3. Being between the ages of 19-65
4. Not having severe psychiatric illness
5. Being fed orally
6. Volunteering to participate in the study for Patients Waiting on the Transplant List

Exclusion Criteria

1. To be removed from the Lung Transplant List
2. Being pregnant or lactating
3. Severe psychiatric illness
4. Peg or Jeg feeding (unable to feed orally)
5. Missing data in the file

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Group 1	Lung transplantation	Ex patients on the lung transplant waiting list
Group 2	Lung transplantation	Tansplant patients
Group 3	Lung transplantation	Patients waiting on the current list

Primary Outcome Measures

Name	Time	Method
BMI	For one month period	BMI values are evaluated for the patients for patients waiting on the transplant list, transplanted and exited.

Secondary Outcome Measures

Name	Time	Method
Nutrition risk index	For one month period.	BMI values are evaluated for the patients for patients waiting on the transplant list, transplanted and exited.

Trial Locations

Locations (1)

OkanU; 🇹🇷 Istanbul, Turkey