The effect of vitamin D deficiency treatment on chronic obstructive pulmonary diseasepatients
Not Applicable
- Conditions
- Chronic Obstructive Pulmonary Disease.Other chronic obstructive pulmonary disease
- Registration Number
- IRCT2013072114085N2
- Lead Sponsor
- Vice chancellor of research ,Guilan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
The inclusion of study criteria are as following : the proof of COPD diagnosis according to clinical conditions and its approval with spirometry based on GOLD ; low serum levels of 25-hydroxyvitamin D (10-30) as insufficiency. The study exclusion criteria : hypercalcemia ; ca more than10.3 ; sarcoidosis (according to diagnosis and clinical examination of pulmonary subspecialty ; cancer (asking the patient) ; osteoprosis that has recently been diagnosed (asking the patient) ; long term use of azithromycin (asking the patient) ; serum 25-hydroxy vitamin D levels less than 10 as deficiency ; thyroid and parathyroid diseases.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The rate of change in COPD stage according to GOLD stages. Timepoint: The time of study inclusion and one month later and 6 months later. Method of measurement: Spirometry.;Evaluation of quality of life of patients. Timepoint: The time of study inclusion and one month later and 6 months later. Method of measurement: CAT Questionnair.;Serum levels of 25-hydroxyvitamin D. Timepoint: The time of study inclusion and one month later and 6 months later. Method of measurement: Measurement of serum levels of 25-hydroxyvitamin D.
- Secondary Outcome Measures
Name Time Method Mortality. Timepoint: During study. Method of measurement: Recording in patients’ information forms.;The duration of taking Systemic steroids and antibiotics. Timepoint: During the study. Method of measurement: Recording in patients’ information forms.;Number of exacerbations. Timepoint: duringt study. Method of measurement: recording in patients’ information forms.;The median time of the occurrence of the first exacerbation during the study. Timepoint: during study. Method of measurement: recording in patients’ information forms.