A comparative study of neuromuscular relaxant effects of remimazolam anesthesia in young and elderly patients.
Phase 1
Recruiting
- Conditions
- Patients undergoing general anesthesia
- Registration Number
- JPRN-jRCT1031230514
- Lead Sponsor
- Takagi Shunichi
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
1. Patients whose age is between 20 and 45 years old or between 70 and 91 years old
2. Patients with an American Society of Anesthesiologists pre-anesthesia risk rating of 3 or less
3. Patients who have given consent
Exclusion Criteria
1. Patients with a history of allergy to muscle relaxants or antagonists
2. Patients with severe complications
3. patients with neuromuscular disease
4. Patients taking medications that may affect the effect of muscle relaxation.
5. Patients who are deemed inappropriate as research subjects by the principal investigator
6. Patients who refuse to participate in the study.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method PTC appearance time in the young and elderly groups
- Secondary Outcome Measures
Name Time Method T1 and T2 appearance time<br>Time until TOF ratio reaches 100% after sugammadex administration<br>PTC, blood rocuronium/remimazolam concentration at T1 and T2 appearance, and rocuronium protein binding rate