Hemophilia and Atherosclerotic Plaque Imaging: an exploratory study
Recruiting
- Conditions
- hemophiliaatherosclerosis3T MRIPlaque vulnerability
- Registration Number
- NL-OMON23229
- Lead Sponsor
- MCG
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 40
Inclusion Criteria
Hemophilia A or B patients:
1. Males, 18 years and older
Exclusion Criteria
Patients and controls:
Patients with symptomatic carotid atherosclerotic disease.
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary objective is to assess carotid artery plaque constitution in terms of intraplaque hemorrhage and plaque burden (thickness) as measured with 3T MRI in both hemophilia patients and control patients.
- Secondary Outcome Measures
Name Time Method To analyze whether the severity of hemophilia affects plaque composition and whether traditional cardiovascular risk factors are important mediators