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Gamified Adaptive Approach Bias Modification on Individuals With Methamphetamine Use History

Not Applicable
Completed
Conditions
Addiction, Substance
Interventions
Behavioral: Static Approach Bias Modification
Behavioral: Adaptive Approach Bias Modification
Registration Number
NCT05794438
Lead Sponsor
Adai Technology (Beijing) Co., Ltd.
Brief Summary

A randomized controlled trial will be conducted to investigate whether a proposed algorithm that adjusts the congruency ratio based on the user's performance and difficulty can enhance the effectiveness of approach bias modification. Methamphetamine users will be recruited and randomized into an algorithm group, a standard group, and a control group.

Detailed Description

To assess the efficacy of an adaptive approach bias modification (A-ApBM) paradigm with gamified designs and dynamic difficulty adjustments in reducing cue-induced craving in individuals with methamphetamine use history. DESIGN: Randomized controlled trial with three study groups: Adaptive ApBM (A-ApBM), Static ApBM (S-ApBM), and control. A-ApBM and S-ApBM groups engaged in ApBM training using a smartphone application for four weeks. A-ApBM used an adaptive algorithm to dynamically adjust the difficulty level based on individual performance, while S-ApBM had a static difficulty level. Cue-induced craving scores were assessed using a visual analog scale at baseline, post-intervention, and at week-16 follow-up.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
139
Inclusion Criteria

• having a history of methamphetamine use of at least one year

Exclusion Criteria
  • could not fluently operate an Android or an iOS smartphone
  • having mental health conditions other than MUD

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Static Approach Bias ModificationStatic Approach Bias Modification-
Adaptive Approach Bias ModificationAdaptive Approach Bias Modification-
Primary Outcome Measures
NameTimeMethod
Cue induced craving for methamphetamine16 week from baseline assesment

The cue-induced craving was assessed by showing the participants images related to methamphetamine (methamphetamine crystals, powders, and paraphernalia) on a smartphone and asking them to rate their cravings on a 0-10 visual analog scale (0 being least craved and 10 being most craved).

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (12)

Sanxingdui Town Community Drug Rehabilitation Center

🇨🇳

Guanghan, Sichuan, China

Gao Ping Town Community Drug Rehabilitation Center

🇨🇳

Guanghan, Sichuan, China

Han Zhou Street Community Drug Rehabilitation Center

🇨🇳

Guanghan, Sichuan, China

Jin Lun Town Community Drug Rehabilitation Center

🇨🇳

Guanghan, Sichuan, China

Jin Yan Street Community Drug Rehabilitation Center

🇨🇳

Guanghan, Sichuan, China

Jin Yu Town Community Drug Rehabilitation Center

🇨🇳

Guanghan, Sichuan, China

Nan Feng Town Community Drug Rehabilitation Center

🇨🇳

Guanghan, Sichuan, China

Lian Shan Town Community Drug Rehabilitation Center

🇨🇳

Guanghan, Sichuan, China

San Shui Town Community Drug Rehabilitation Center

🇨🇳

Guanghan, Sichuan, China

SixTwentySix Service Center, Luo Cheng Street, Guanghan City

🇨🇳

Guanghan, Sichuan, China

Xiang Yang Town Community Drug Rehabilitation Center

🇨🇳

Guanghan, Sichuan, China

Xiao Han Town Community Drug Rehabilitation Center

🇨🇳

Guanghan, Sichuan, China

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