To compare the efficacy of Opioid free analgesia with Magnesium sulphate and Ketamine versus opioid analgesia with Morphine in perioperative period for head and neck oncosurgeries by total intravenous anaesthesia technique.
Phase 4
- Conditions
- Health Condition 1: C06- Malignant neoplasm of other and unspecified parts of mouth
- Registration Number
- CTRI/2022/12/048378
- Lead Sponsor
- Sreya Ramachandran
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
ASA 1 OR 2 , undergoing elective head and neck oncosurgey.BMI between 18 to 35Kg/m2. who are ready to give written informed consent
Exclusion Criteria
Patient refusal , ASA 3 and 4 patients , pregnants ,lactating mothers ,deteriorating neurological disorders ,liver disease, renal disease ,cardiovascular disease with EF less than 40.known drug allergy.chronic pain on opioid or other analgesic .calcium channel blocker treatment
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Perioperative analgesia. <br/ ><br>Timepoint: 0 hours to 48 hours of surgery. <br/ ><br>
- Secondary Outcome Measures
Name Time Method intraoperative haemodynamic stability.Timepoint: 24 hours