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Clinical Trials/NCT02217696
NCT02217696
Unknown
Not Applicable

Neuronal Markers of Grapheme-phoneme Training Response for Prediction of Successful Reading Acquisition in Children at Familial Risk for Developmental Dyslexia

University of Zurich1 site in 1 country110 target enrollmentStarted: July 2013Last updated:

Overview

Phase
Not Applicable
Enrollment
110
Locations
1
Primary Endpoint
Changes in reading and spelling performance

Overview

Brief Summary

The long-term goal of this study is to improve prediction of poor reading outcome at preschool age by using a combination of behavioural and neuroimaging measures and to evaluate a specific computerized training program to support children with problems during reading acquisition.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Crossover
Primary Purpose
Basic Science
Masking
Single (Outcomes Assessor)

Eligibility Criteria

Ages
5 Years to 9 Years (Child)
Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Changes in reading and spelling performance

Time Frame: Participants will be tested at three times for the duration of the cross-sectional intervention, an expected average of 8 months

Performance in normed reading and/or spelling (standardized tests) as a result of reading acquisition and training

Secondary Outcomes

  • Developmental and training induced changes in functional brain activation and brain structure(Participants will be tested after an expected average of 8, 12 and 16 months)
  • Accuracy of prediction on reading performance outcome(Participants will be tested at T1 and on average 8 months later)

Investigators

Sponsor Class
Other
Responsible Party
Sponsor

Study Sites (1)

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