Prediction and Intervention in Developmental Dyslexia

Not Applicable

• Conditions: Developmental Dyslexia
• Interventions: Other: Computerized reading training

• Registration Number: NCT02217696
• Lead Sponsor: University of Zurich

Brief Summary

The long-term goal of this study is to improve prediction of poor reading outcome at preschool age by using a combination of behavioural and neuroimaging measures and to evaluate a specific computerized training program to support children with problems during reading acquisition.

Detailed Description

Not available

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Study Start: 2013-07
• Status Verified: 2014-08
• Study First Submitted: 2014-08-08
• Study First Submitted QC: 2014-08-13
• Last Update Submitted: 2014-08-13
• Study First Posted: 2014-08-15
• Last Update Posted: 2014-08-15
• Primary Completion: 2018-07
• Study Completion: 2018-07

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 110

Inclusion Criteria

Not provided

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Exclusion Criteria

Not provided

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Computerized reading training first	Computerized reading training	Cross-over design: group first receives the intervention
Waiting Control First	Computerized reading training	Cross-over design: group first serves as waiting control

Primary Outcome Measures

Name	Time	Method
Changes in reading and spelling performance	Participants will be tested at three times for the duration of the cross-sectional intervention, an expected average of 8 months	Performance in normed reading and/or spelling (standardized tests) as a result of reading acquisition and training

Secondary Outcome Measures

Name	Time	Method
Developmental and training induced changes in functional brain activation and brain structure	Participants will be tested after an expected average of 8, 12 and 16 months	Changes in activation/structure of core language network regions assessed by EEG and MRI during development, learning and training
Accuracy of prediction on reading performance outcome	Participants will be tested at T1 and on average 8 months later	Accuracy of prediction on reading performance (standardized tests) using behavioural and/or neuroimaging measures.; Neuroimaging measures: EEG and MRI (functional activation, structural measures from white and/or grey matter, temporal information from event-related potential and/or frequency analyses)

Trial Locations

Locations (1)

University Clinics for Child and Adolescent Psychiatry, University of Zurich; 🇨🇭 Zurich, Switzerland