USG-Guided Infiltration Popliteal Artery Capsule Knee Block Versus Adductor Canal Block Application as Postoperative Analgesia

Phase 4

Completed

• Conditions: Postoperative Pain
• Interventions: Drug: Tramadol; Drug: Morfin

• Registration Number: NCT05956275
• Lead Sponsor: Siirt Training and Research Hospital

Brief Summary

The purpose was to evaluate the effect of USG-guided adductor canal block and infiltration popliteal artery capsule knee block combination on postoperative analgesia before total knee arthroplasty.

Detailed Description

In the present study, the purpose was to evaluate the effect of Ultrasound(USG)-guided adductor canal block(ACB) and infiltration popliteal artery capsule knee block(IPACK) combination on postoperative analgesia before total knee arthroplasty(TKA). A total of 40 patients,who were aged 18-75 with the American Society of Anesthesiologists score(ASA) I-III physical status,and who were scheduled for TKA under general anesthesia,were included in the present study.ACB and IPACK were performed in group A(ACB+IPACK) accompanied by USG, Bupivacaine and 10 mL of 0.9% sodium chloride were applied in each block application.No block was applied to the patients in group B.Patient-controlled analgesia was administered to both groups 30 minutes before the end of the surgery.Tramadol HCL was infused at a concentration of 4mg/ml.A bolus of 20 mg of tramadol hydrochloride was given with a lock-in interval of 30 minutes.Postoperative systolic arterial pressure(SAP),diastolic arterial pressure(DAP),mean arterial pressure(MAP),heart rate(HR),visual analog scale(VAS),analgesic consumption,nausea,vomiting, and patient satisfaction scores were recorded.

Study Timeline

• Study Start: 2020-12-08
• Primary Completion: 2021-10-01
• Study Completion: 2021-10-02
• Status Verified: 2023-07
• Study First Submitted: 2023-07-04
• Study First Submitted QC: 2023-07-13
• Last Update Submitted: 2023-07-13
• Study First Posted: 2023-07-21
• Last Update Posted: 2023-07-21

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• aged between 18-75 years
• who were scheduled for elective total knee arthroplasty in Bolu Abant Izzet Baysal University Training and Research Hospital Orthopaedics and Traumatology Clinics

Exclusion Criteria

• Patients with hypersensitivity to the drugs to be used in the study or the substances in their composition
• pregnant women
• severe cardiac, pulmonary, hepatic, and renal disease
• a history of chronic opioid use and chronic pain syndrome
• patients who were not suitable for regional anesthesia (bleeding diathesis, infection in the procedure area), and those who could not apply patient controlled anesthesia

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Control	Morfin	No block performed
adductor canal block and infiltration popliteal artery capsule knee block	Morfin	Adductor canal block and infiltration popliteal artery capsule knee block were performed accompanied by USG, Bupivacaine and 10 mL of 0.9% NaCl were applied in each block application.
adductor canal block and infiltration popliteal artery capsule knee block	Tramadol	Adductor canal block and infiltration popliteal artery capsule knee block were performed accompanied by USG, Bupivacaine and 10 mL of 0.9% NaCl were applied in each block application.
Control	Tramadol	No block performed

Primary Outcome Measures

Name	Time	Method
tramadol consumption	24 hours	tramadol consumption amounts were 0-1 hours, 1-12 hours, 12-24 hours
using morphine as rescue analgesia	24 hours	rescue analgesia was evaluated for 0-1 hour, 1-12 hours, and 12-24, the number of patients who used morphine

Trial Locations

Locations (1)

Bolu Abant İzzet Baysal University; 🇹🇷 Bolu, Turkey