study of transcranial magnetic stimulation effect on motor imagery rehabilitation and movement improvment in multiple sclerosis patients
- Conditions
- multiple sclerosis.
- Registration Number
- IRCT2013042313100N1
- Lead Sponsor
- Kerman medical university-dean of research
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 50
All patients (20 to 40 years old ) met the Mc Donald criteria for diagnosis of MS.All of them belong to relapsing remitting MS subgroup.
The study exclusion criteria included patients with EDSS > 3.5; new clinical attack during 3 months prior to the study; other neurological diseases (stroke, seizure, etc.); head trauma, chronic psychiatric disorder. Patients were right-handed based on the Edinburgh Handedness Inventory. Fatigue score based on Fatigue Severity Scale questionnaire should be less than 37. Depression score based on Beck Depression questionnaire should be less than 21. Mini mental state examination score should be more than 24.
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Mental rotation ability. Timepoint: befor rTMS implementation and after the 10th rTMS session. Method of measurement: Reaction time and accuracy (percent of correct response) were recorded.;Upper limb imagery chronometry. Timepoint: before rTMS implementation and after the 10th rTMS session. Method of measurement: (real performance-motor imagery)/real performance.;Upper limb function. Timepoint: before rTMS implementation and after the 10th rTMS session. Method of measurement: number of moved blocks in 1 minute.;Upper limb function. Timepoint: before rTMS implementation and after the 10th rTMS session. Method of measurement: recorded time for moving nine pegs.;Lower limbs function. Timepoint: before rTMS implementation and after the 10th rTMS session. Method of measurement: recorded time for walking 25 foots.
- Secondary Outcome Measures
Name Time Method