Multicenter Retrospective Database on Prognostic and Predictive Factors in Patients With Neuroendocrine Tumors

Active, not recruiting

• Conditions: Neuroendocrine Tumors; Carcinoma;Endocrine

• Registration Number: NCT05168631
• Lead Sponsor: Latin American Cooperative Oncology Group

Brief Summary

Multicenter retrospective longitudinal analytical study of patients with neuroendocrine tumors.

Detailed Description

Not available

Study Timeline

• Study Start: 2020-05-16
• Study First Submitted: 2021-12-20
• Study First Submitted QC: 2021-12-22
• Study First Posted: 2021-12-23
• Status Verified: 2025-02
• Last Update Submitted: 2025-02-11
• Last Update Posted: 2025-02-12
• Primary Completion: 2025-03-15
• Study Completion: 2025-03-15

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 88

Inclusion Criteria

• Patients aged 18 years or older and with histologically confirmed neuroendocrine tumors;
• Metastatic or inoperable disease;
• Patients with clinical information about the therapies received, including exclusive palliative care.

Exclusion Criteria

• Lack of data on survival outcomes and/or details on treatments received.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Overall survival	2022

Secondary Outcome Measures

Name	Time	Method
Response rate per RECIST 1.1;	2022
Progression-free survival by RECIST 1.1 from D1 of each treatment;	2022
Symptom control time	2022	Improvement of symptoms and/or stabilization of radiological disease in non-functioning ENT, at the physician's discretion
Incidence of complications of the disease and/or treatments, defined by adverse events	2022

Trial Locations

Locations (7)

Ensino E Terapia de Inovacao Clinica Amo - Etica; 🇧🇷 Salvador, Bahia, Brazil

Universidade Federal do Ceará/HOSPITAL UNIVERSITARIO WALTER CANTIDIO; 🇧🇷 Fortaleza, Ceará, Brazil

Hospital Sírio Libanês Brasília; 🇧🇷 Brasília, Distrito Federal, Brazil

Hospital Moinhos de Vento; 🇧🇷 Porto Alegre, Rio Grande Do Sul, Brazil

Fundacao Antonio Prudente - Ac Camargo Center; 🇧🇷 São Paulo, Brazil

Hospital Alemão Oswaldo Cruz; 🇧🇷 São Paulo, Brazil

Instituto Nacional de Enfermedades Neoplàsicas; 🇵🇪 Surquillo, Peru