HART: High-intensity Aerobic and Resistance Training for metabolic syndrome.

Not Applicable

• Conditions: Metabolic syndrome; Metabolic and Endocrine - Metabolic disorders

• Registration Number: ACTRN12619001619134
• Lead Sponsor: SW Sydney

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2018-10-26
• Study Start: 2019-11-22
• Last Update Posted: 10 December 2019

Recruitment & Eligibility

• Status: Stopped early
• Sex: All
• Target Recruitment: 13

Inclusion Criteria

Adult males and females over the age of 18 who meet the IDF/AHA (2009) criteria for diagnosis of the metabolic syndrome.

Exclusion Criteria

• Adults with diagnosed cardiovascular disease, renal disease or diabetes.
• Adults who display an abnormal response to intense exercise (as seen during the exercise test).
• Adults who are unable to speak English and do not have a translator.
• Adults with orthopedic or neuromuscular limitations or self-perceived reasons that prevent them from performing the prescribed exercise.
• Adults who are unable to climb stairs or walk on flat ground at a moderate to high intensity (>70% maximum heart rate)

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change in cardiorespiratory fitness, indicated by VO2peak, measured via indirect calorimetry during a graded exercise test on the treadmill. VO2peak will be measured with a gas exchange mask and Medgraphics Ultima metabolic cart. The graded exercise test will follow the modified Bruce protocol. The value used in statistical analysis will be the highest 15-second average during the last minute of exercise, where heart rate >85% age-predicted maximum heart rate and respiratory exchange ratio >1.0.[pre-intervention commencement and ~1 week post-intervention.]