ow volume high-intensity resistance training in type 2 diabetes: effects on glycemic control.
- Conditions
- Diabetestype 2 Diabetes mellitus (T2DM)10018424
- Registration Number
- NL-OMON41594
- Lead Sponsor
- Stichting Thuiszorg West-Brabant
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Withdrawn
- Sex
- Not specified
- Target Recruitment
- 118
(1) Diagnosis of T2DM by the American Diabetes Association criteria, i.e. a) HbA1c >=6.5%, or b) fasting plasma glucose >=7.0 mmol/L, or c) 2-h plasma glucose >=11.1 mmol/L.
(2) Baseline HbA1c value of 6.6% to 9.9% (normal range, 4.0% to 6.0%).
(3) Minimum age of 18 years.
(1) Current insulin therapy.
(2) Participation in exercise 2 or more times weekly for 20 minutes or longer per session or in any resistance training during the previous 6 months.
(3) Insufficient mastery of the Dutch language.
(4) Cognitive impairment
(5) Changes during the previous 2 months in oral hypoglycemic, antihypertensive,or lipid-lowering agents or body weight (>=5%).
(6) Serum creatinine level of 200 µmol/L or greater (>=2.26 mg/dL).
(7) Proteinuria greater than 1 g/d.
(8) Blood pressure greater than 160/100 mm Hg.
(9) Restrictions in physical activity because of disease.
(10) Presence of other medical conditions that made participation inadvisable.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>(1) glycemic control<br /><br>The absolute change in plasma glycosylated haemoglobin concentration (HbA1c<br /><br>[%]) from baseline to the end of the intervention period between both groups<br /><br>will be assessed as main outcome for glycemic control. In addition fasting<br /><br>plasma glucose (mmol/L) will be assessed.</p><br>
- Secondary Outcome Measures
Name Time Method