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Clinical Trials/NCT06149299
NCT06149299
Recruiting
Not Applicable

Comparison of Pain Relief and Block Success of Great Occipital Nerve Block Using Different Approach Method at C2 Level

Keimyung University Dongsan Medical Center1 site in 1 country24 target enrollmentNovember 13, 2023
ConditionsPain, Chronic

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Pain, Chronic
Sponsor
Keimyung University Dongsan Medical Center
Enrollment
24
Locations
1
Primary Endpoint
block success
Status
Recruiting
Last Updated
2 years ago

Overview

Brief Summary

Great occipital nerve (GON) block is commonly applied for the pain management of occipital neuralgia, migraine, and cervicogenic headache. The GON orginates from the medial branch of the dorsal ramus of the C2 spinal nerve with variable contribution from the C3 dorsal ramus. After emerging from the suboccipital triangle, the nerve courses cephalad in an oblique trajectory between the semispinalis capitis (SC) and obliqus capitis inferior (OCI) muscles. This area was recognized as a potential location for GON injury. The nerve then passes through the trapezius muscle and courses medial to the occipital artery as it ascends to innervate the posterior scalp.

Many practitioners perform GON injections using a conventional approach, relying solely on superficial bone-based anatomic landmarks to infiltrate local anesthetic and corticosteroid around the nerve at the level of the superior nuchal line.

Some clinicians also use fluoroscopy to confirm the location of bony landmarks. The ambiguity of these injections poses a risk of anesthetizing adjacent structures or injecting into vessels, such as the occipital artery. Very limited research has been done to quantify the risk of these injections, but a complication rate of 5% to 10% has been reported, including headache, dizziness, blurred vision, and syncope.

Ultrasound guidance is increasingly used to mitigate these risks and improve the efficacy of GON injections. Multiple studies have demonstrated successful ultrasound-guided GON blockade at the superior nuchal line and improvement in pain scores compared with nonguided injections.

C2 level GON block using ultrasound targets interfascial plane between OCI and SC muscles. However, a pain physician who begins ultrasound guided injections migth feel very difficult targeting interfascial plane exactly.

Since GON orginiates from deep space of suboccipital triangle, it is expected that injection within OCI muscle might have similar effect with the effect of injection into interfascial plane.

We assume that if the local anesthetics is injected within OCI muscle, the effect of GON block will be generated by the diffusion of injected local anesthetics.

Registry
clinicaltrials.gov
Start Date
November 13, 2023
End Date
June 30, 2024
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Ji Hee Hong

Professor

Keimyung University Dongsan Medical Center

Eligibility Criteria

Inclusion Criteria

  • Cervicogenic headache
  • Occipital neuralgia

Exclusion Criteria

  • bilateral headache
  • cervical spine surgery within 1 year before
  • loss of sensory sensation at the dermatome of GON innervation
  • anatomical defect at the region of procedure
  • coagulopathy
  • pregnancy or breast feeding
  • allergy to local anesthetics

Outcomes

Primary Outcomes

block success

Time Frame: Baseline, 30 minutes after the completion of GON block

block success after GON block

Numerical rating scale

Time Frame: Baseline, 30 minutes, 2 weeks, 4 weeks after the completion of GON block

Numerical rating scale after GON block

Secondary Outcomes

  • Side effect after GON block(Baseline, 30 minutes after the completion of GON block)

Study Sites (1)

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