Determining the minimum dose required of Remifentanil to obtain adequate intubating conditions in children presenting for day case surgery - a randomised controlled trial
- Conditions
- Anaesthesia
- Registration Number
- PACTR201809879218534
- Lead Sponsor
- niversity of Pretoria Faculty of Health Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 60
Inclusion criteria include: Patients aged three to ten years of age,
Elective dental/maxillofascial surgery,
ASA 1 and 2 patients,
Patients fasted according to current guidelines (Milk and solid food is six hours; breastmilk is four hours; clear fluids is two hours)
Exclusion criteria is as follows: Parental/guardian refusal
Patient refusal,
If the patient is allergic to any of agents used in this study,
Patient not in specified age group,
Bacterial or viral upper/lower respiratory tract infection,
Difficult airway,
Patients known with or a family history of anaesthetic complications such as porphyria or malignant hyperthermia,
Patients known with obstructive sleep apnoea or at risk of developing obstructive sleep apnoea,
Patients with heart murmurs that have not yet been investigated and diagnosed,
Patients with congenital heart disease,
Any patient at risk of aspiration (due to not being starved or due to a medical condition such as diabetes mellitus)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To determine the minimum required dose of remifentanil needed for intubation in children presenting for day case surgery without the use of neuromuscular blocking agent
- Secondary Outcome Measures
Name Time Method To determine the dose of remifentanil for effective intubation with the least haemodynamic interference.