Assisted Hatching Versus Endometrial Scratch in Recurrent Implantation Failure

Not Applicable

• Conditions: Recurrent Implantation Failure

• Registration Number: NCT02752568
• Lead Sponsor: Kasr El Aini Hospital

Brief Summary

300 recurrent implantation failure patients will be alternatively assigned to assisted hatching , endometrial scratch , and no treatment ,100 patients in each group

Detailed Description

Group 1 consists of 100 patients will undergo endometrial scratch followed by controlled ovarian hyperstimulation Group 2 consists of 100 patients will undergo controlled ovarian hyperstimulation\& assisted hatching Group 3 consists of 100 patients will undergo controlled ovarian hyperstimulation

Study Timeline

• Status Verified: 2016-04
• Study First Submitted: 2016-04-25
• Study First Submitted QC: 2016-04-26
• Last Update Submitted: 2016-04-26
• Study First Posted: 2016-04-27
• Last Update Posted: 2016-04-27
• Study Start: 2016-05
• Primary Completion: 2016-11
• Study Completion: 2016-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Female
• Target Recruitment: 300

Inclusion Criteria

• recurrent implantation failure
• normal uterine cavity by transvaginal ultrasound

Exclusion Criteria

• endometrial polyp or fibroid distorting the endometrium
• hydrosalpinx
• preimplantation genetic diagnosis
• severe male factor

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: FACTORIAL

Primary Outcome Measures

Name	Time	Method
number of patients with positive pregnancy test	2 months