Correlation of Atherogenic Index of Plasma with Stenosis level of Coronary Artery in Acute Coronary Syndrome
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- Correlation between Atherogenic Index of Plasma to severity of CAD in patients undergoing coronary angiogram.
研究概览
简要总结
AIM- To evaluate the role of the AIP in Acute coronary Syndrome and correlate with stenosis of coronary artery.
Objectives:
-To correlate AIP with severity of coronary artery disease as assessed by extent of stenosis in coronary angiogram and number of vessels involved.
-To study clinical and metabolic profile of patients with coronary artery disease.
Description of procegure: Based on the results of coronary angiography, 2 groups will be established.
- Patients In CAD Significant group will be defined as those having angiographic coronary stenosis of at least >= 50% lumen reduction in at least one major coronary artery
-Patients with luminal stenosis but less than <50% will be defined as CAD insignificant group.
AIP will be calculated for both the groups by using the equation- log [Triglyceride]/[HDL cholesterol]
Outcomes will be classified as following: low risk: AIP<0.11, Intermediate Risk: AIP= 0.11-0.21, High Risk: AIP> 0.21
Outcomes will be correlated with % of stenosis and number of vessels involved to assess the severity.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 99.00 Year(s)（—）
- 性别
- All
入选标准
- •1 Adults above the age of (18 )years of age, posted for coronary angiogram for suspected ischemic heart disease(acute coronary syndrome) at Kasturba hospital, Manipal.
排除标准
- •1 Patients below (18) years of age 2 History of percutaneous transluminal coronary angioplasty/coronary artery bypass graft 3 Chronic liver Disease 4 Chronic Kidney Disease 5 History of Stroke 6 Patients with RVD 7 Autoimmune disease 8 Patients with malignancy.
结局指标
主要结局
Correlation between Atherogenic Index of Plasma to severity of CAD in patients undergoing coronary angiogram.
时间窗: Outcome will be assessed at baseline
To study the clinical and metabolic profile of patients with coronary artery disease.
时间窗: Outcome will be assessed at baseline
次要结局
- To Study the clinical and metabolic profile of patients with coronary artery disease(cross-sectional study)
研究者
Dr Sunkara Divya Venkata Sagar
Kasturba Medical College, Manipal