Microbial Community Transplantation on the Armpit/Foot

Not Applicable

Completed

• Conditions: Heavy, Bad Body Odour From Armpit; Heavy, Bad Body Odour From Foot
• Interventions: Biological: Microbial transplant

• Registration Number: NCT01581112
• Lead Sponsor: University Ghent

Brief Summary

The malodour generation of a person's armpit/foot is caused by the bacteria thriving on that armpit/foot. In order to alter or reduce once bad body odour or foot odour, the living microbial community on the foot/armpit of a non-malodorous person will be transmitted (or up scaled and transmitted) to the foot/armpit of a malodorous person. The odour is evaluated by a trained smelling panel, the bacteria living on the armpit/foot is examined by means of molecular techniques. The microbial transplantation and its follow-up happens under the supervision of a doctor.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2012-04-18
• Study First Submitted QC: 2012-04-18
• Study First Posted: 2012-04-19
• Study Start: 2012-09
• Primary Completion: 2013-05
• Study Completion: 2013-06
• Status Verified: 2013-09
• Last Update Submitted: 2013-09-17
• Last Update Posted: 2013-09-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 4

Inclusion Criteria

• Bad armpit or foot odour

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Heavy armpit odour	Microbial transplant	Subjects with heavy armpit odour.
Heavy foot odour	Microbial transplant	Subjects with heavy foot odour.

Primary Outcome Measures

Name	Time	Method
Change in odour severity after bacterial transplantation	Baseline and week 4	Odour evaluation by a trained smelling panel.
Change in molecular characterisation of the bacterial community.	Baseline and week 4	Microbial evaluation by means of DNA extraction and Denaturing Gradient Gel Electrophoresis (DGGE).

Secondary Outcome Measures

Name	Time	Method
Change in molecular characterisation of the bacterial community	Baseline and 6 months	Microbial evaluation by means of DNA extraction and Denaturing Gradient Gel Electrophoresis (DGGE).
Change in odour severity after bacterial transplantation	Baseline and 6 months	Odour evaluation by a trained smelling panel.

Trial Locations

Locations (1)

Ghent University; 🇧🇪 Ghent, Belgium