Effect of anahealbormelain on clinical parameters of periodontal in non-surgical paients with chronic periodontitis

Phase 3

Completed

• Conditions: Patients with chronic periodontitis.; Chronic periodontitis

• Registration Number: IRCT2017051114440N3
• Lead Sponsor: Department of Periodontics of Dental Faculty of Tabriz University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

Patients who suffer from moderate chronic periodontitis with clinical attachment loss (CAL) of 3 to 4 millimeters who were systemically healthy.
Exclusion criteria :
Sensitivity to the medication (patients with sensitivity to pineapple, celery, carrot and fennel may also have sensitivity to Bromelain),History of cardiac diseases, Pregnant women, Gastrointestinal diseases such as peptic ulcer, Renal or Hepatic Diseases, coagulated anomalies such as hemophilia, Systemic lupus erythematous, Any history of periodontal treatment (scaling, root planning or surgery) at the past six months, Alcohol, cigarette or drug consumption, Concurrent Anti-coagulant or thrombolytic therapy

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
CAL (clinical attachment level). Timepoint: before the intervention, four weeks after initiating the intervention and eight weeks after initiating the intervention. Method of measurement: measurement of the distance between the stent margin to the sulcus base by means of a periodontal probe.

Secondary Outcome Measures

Name	Time	Method
Plaque. Timepoint: Before the intervention, four weeks after initiating the intervention and eight weeks after initiating the intervention. Method of measurement: by disclosing agent with visual scale.;Bleeding on probing(BOP). Timepoint: before the intervention, four weeks after initiating the intervention and eight weeks after initiating the intervention. Method of measurement: bleeding in 15 seconds after gentle probing by periodontal probe.;Probing depth(PD). Timepoint: Before the intervention, four weeks after initiating the intervention and eight weeks after initiating the intervention. Method of measurement: The distance between the mucosal margin and the sulcus base by periodontal probe in millimeters.;Gingival index(GI). Timepoint: before the intervention, four weeks after initiating the intervention and eight weeks after initiating the intervention. Method of measurement: observation of index score.