Endometrial receptivity with different support protocols for the luteal phase in ovarian stimulation cycles in which final oocyte maturation is carried out with GnRH analogues. Analysis by endometrial microarrays.
- Conditions
- Ovarian Hyperstimulation Syndrome (OHSS)MedDRA version: 14.0Level: PTClassification code 10033266Term: Ovarian hyperstimulation syndromeSystem Organ Class: 10038604 - Reproductive system and breast disordersTherapeutic area: Body processes [G] - Reproductive physiologi cal processes [G08]
- Registration Number
- EUCTR2011-003250-34-ES
- Lead Sponsor
- IVI Madrid
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Authorised-recruitment may be ongoing or finished
- Sex
- Female
- Target Recruitment
- Not specified
1.Aged between 18 and 34 years old.
2.Ovule donors admitted in the IVI Oocyte Donor Program - Madrid.
3.Conventional ovarian stimulation protocol.
4.Normal XX karyotype.
5.Body mass index (BMI) between 18 and 25 kg / m2.
6.Negative serologies for Hepatitis B surface antigens (HBs Ag), antibodies for the Hepatitis C virus (HC Hb) and Human Immunodeficiency Virus (HIV) prior to donation.
7.Normal cervical cytology in the past year.
8.General informed consent signed by the patients or their legal representative.
Are the trial subjects under 18? no
Number of subjects for this age range: 0
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 25
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range
1.Any clinical condition that counterindicates or prevents being able to carry out an endometrial biopsy.
2.Hypersensitivity, allergy or intolerance to any of the medications prescribed in each of the treatment groups.
3.Participation in another clinical trial at the time of donation.
4.Any serious concomitant illness which, according to investigator´s opinion, may compromise the study or affect patients´ tolerability with regard to this treatment.
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method