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Endometrial receptivity with different support protocols for the luteal phase in ovarian stimulation cycles in which final oocyte maturation is carried out with GnRH analogues. Analysis by endometrial microarrays.

Conditions
Ovarian Hyperstimulation Syndrome (OHSS)
MedDRA version: 14.0Level: PTClassification code 10033266Term: Ovarian hyperstimulation syndromeSystem Organ Class: 10038604 - Reproductive system and breast disorders
Therapeutic area: Body processes [G] - Reproductive physiologi cal processes [G08]
Registration Number
EUCTR2011-003250-34-ES
Lead Sponsor
IVI Madrid
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Authorised-recruitment may be ongoing or finished
Sex
Female
Target Recruitment
Not specified
Inclusion Criteria

1.Aged between 18 and 34 years old.
2.Ovule donors admitted in the IVI Oocyte Donor Program - Madrid.
3.Conventional ovarian stimulation protocol.
4.Normal XX karyotype.
5.Body mass index (BMI) between 18 and 25 kg / m2.
6.Negative serologies for Hepatitis B surface antigens (HBs Ag), antibodies for the Hepatitis C virus (HC Hb) and Human Immunodeficiency Virus (HIV) prior to donation.
7.Normal cervical cytology in the past year.
8.General informed consent signed by the patients or their legal representative.
Are the trial subjects under 18? no
Number of subjects for this age range: 0
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 25
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

1.Any clinical condition that counterindicates or prevents being able to carry out an endometrial biopsy.
2.Hypersensitivity, allergy or intolerance to any of the medications prescribed in each of the treatment groups.
3.Participation in another clinical trial at the time of donation.
4.Any serious concomitant illness which, according to investigator´s opinion, may compromise the study or affect patients´ tolerability with regard to this treatment.

Study & Design

Study Type
Interventional clinical trial of medicinal product
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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