ORAL ZINC SUPPLEMENTATION FOR ACUTE DIARRHEA IN CHILDREN OLDER THAN 5 YEARS

Phase 3

Completed

• Conditions: Health Condition 1: null- Acute dehydrating diarrhoea in children more than 5 years ageHealth Condition 2: A09- Infectious gastroenteritis and colitis, unspecified

• Registration Number: CTRI/2011/06/001807
• Lead Sponsor: Intramural research grant University College of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2012-04-30
• Last Update Posted: 17 October 2022

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 134

Inclusion Criteria

Children aged 5-12 years presenting to pediatric casualty with acute watery diarrhea (3 or more episodes of loose stools over previous 24 h) of less than 72 hours duration, with some or severe dehydration will be included as the study population.

Exclusion Criteria

1)Dysentery (blood in stools)

2)Coexisting severe systemic illness

3)Received any zinc containing multivitamin / mineral supplementation for 7 days in last 3 months

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Duration of diarrheaTimepoint: Duration of diarrhea defined as the time for clinical resolution of diarrhea.

Secondary Outcome Measures

Name	Time	Method
1.Number of days with watery stools <br/ ><br>2.Clinical recovery <br/ ><br>3.Amount of fluids needed <br/ ><br>4.Time taken for rehydration <br/ ><br>5.Recurrence in next 3 monthsTimepoint: 1.Number of days with watery stools: A day with watery stools will be defined as the passage of three or more watery stools in 24 hrs <br/ ><br>2.Clinical recovery: defined as resolution of diarrhea within 72 hours after the start of therapy. <br/ ><br>3.Amount of fluids needed (ORS or intravenous fluids) <br/ ><br>4.Time taken for rehydration: from enrolment to complete rehydration (hydration retained for at least 24 hours) <br/ ><br>5.Recurrence in next 3 months: number of episodes of acute diarrhea <br/ ><br>