Fundoscopy to assess evidence of microvascular thrombosis in cardiac surgery
- Conditions
- Changes in microcirculation post cardiac surgeryInflammatory and Immune System - Other inflammatory or immune system disorders
- Registration Number
- ACTRN12607000648426
- Lead Sponsor
- St Vincents Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot yet recruiting
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
Patients undergoing cardiac surgery
Exclusion Criteria
Previous cardiac surgery; eye disease; patient refusal; type 1 Diabetes Mellitus
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To assess changes eg emboli and inflammatory changs in the retinal circulation post cardiac surgery. No other instruments besides retinal photographs will be used[1 day post operatively]
- Secondary Outcome Measures
Name Time Method The retinal photographs will be assessed by researchers in ophthalmology who will measure the diameter and patency of the retinal blood vessels. Secondary outcomes may be any other incidental changes in the retina, such as evidence of oedema, post cardiac surgery.[1 day post operatively]
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms link post-cardiac surgery microvascular thrombosis to systemic inflammation in ACTRN12607000648426?
How does fundoscopy-based microvascular assessment compare to OCT or retinal imaging in cardiac surgery outcomes?
Which inflammatory biomarkers correlate with microcirculatory changes detected by fundoscopy in cardiac surgery patients?
What adverse events are associated with fundoscopy monitoring in post-cardiac surgery microvascular thrombosis studies?
Are anticoagulant or anti-inflammatory agents being evaluated in combination with fundoscopy for microvascular thrombosis prevention in ACTRN12607000648426?