Method for prevention of oxytocin-induced hypotension in caesarean delivery by mixing of phenylephrine with oxytoci

Completed

• Conditions: Elective caesarean section under spinal anaesthesia; Pregnancy and Childbirth; Delivery by elective caesarean section

• Registration Number: ISRCTN71886984
• Lead Sponsor: Ministry of Health (Brunei)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2012-04-04
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 200

Inclusion Criteria

1. American Society of Anesthesiologists (ASA) class l and ll undergoing elective caesarean section
2. Age between 18 to 35 years
3. Body mass index (BMI) less than 35 kg/m2
4. Spinal anaesthesia

Exclusion Criteria

1. Placenta previa
2. Thrombocytopenia
3. Coagulopathies
4. Previous major obstetrics haemorrhage (more than 1000 ml)
5. Known fibroid
6. Receiving anticoagulant therapy
7. Anemia (hemoglobin less than 9 g/dl)
8. Body mass index greater than 35 kg/m2
9. Preeclampsia
10. Cardiac, respiratory and renal disease
11. Known allergy to any protocol medicine

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Percentage drops in blood pressure (BP) below 20% of baseline after intravenous injection of oxytocin in each arm of study

Secondary Outcome Measures

Name	Time	Method
Percentage of patient having nausea and vomiting after oxytocin in each arm of study