Does a combination of fluid restriction and the use of oxytocin in a pulsatile fashion (intermittent boluses) for women requiring an induction, result in a reduction in the duration of labour, defined by the commencement of oxytocin until the birth of the neonate, when compared to a regime of fluid restriction with continuous oxytocin?

Phase 4

• Conditions: Reproductive Health and Childbirth - Antenatal care; Reproductive Health and Childbirth - Childbirth and postnatal care; abour (induction of); Labour (induction of); Childbirth; Reproductive Health and Childbirth - Fetal medicine and complications of pregnancy

• Registration Number: ACTRN12623000238673
• Lead Sponsor: orthern Health

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2023-03-06
• Last Update Posted: 13 March 2023

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: Female
• Target Recruitment: 412

Inclusion Criteria

Any of the indications for induction of labour as per institutional policy including the following:
Diabetes (Type I, Type II, gestational diabetes, which is poorly controlled)
Hypertension
Pre-eclampsia
Prolonged pregnancy defined as being greater than 41 weeks and 3 days
Term prolonged rupture of membranes
Reduced fetal movements +/- non-reassuring CTG
Past history of fetal death in utero
Chorioamnionitis
Low PAPP-A
Advanced maternal age (defined as greater than or equal to 40 years of age)
Blood group isoimmunisation
Suspected intrauterine growth restriction

Exclusion Criteria

Age less than 18 years
Women who do not have the mental and/or legal capacity to consent
Fetal presentation other than cephalic
Gestational age < 37 weeks
Multiple pregnancy
Augmentation of labour

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The primary outcome is the duration of labour as defined by the commencement of oxytocin, until the birth of the neonate. The time of commencement of oxytocin is documented in the participant's medical record, as is the time of birth of the neonate. The elapsed time between these two time points will be calculated in minutes, thus providing the duration of labour, in minutes.[The primary timepoint is the birth of the neonate.]