Efficacy evaluation of auricular acupuncture combined with intravenous infusion therapy in the treatment of pregnancy nausea and vomiting: A protocol of randomized controlled trial
Phase 1
- Registration Number
- TCTR20220331005
- Lead Sponsor
- Ya Zou
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending (Not yet recruiting)
- Sex
- All
- Target Recruitment
- 45
Inclusion Criteria
1.Patients consistent with the diagnosis of pregnancy nausea and vomiting 2.Age: 18 to 40 years old 3.Patients who has positive urine pregnancy test 4.Patients with intrauterine pregnancy showed by B ultrasound; Patients with 7 to 14 weeks of gestation 5.Patients whose liver function and kidney function are normal.
Exclusion Criteria
1.Patients who had a history of severe nausea and vomiting before pregnancy 2.Patients with gastroenteritis, biliary tract infection, hepatitis, appendicitis and other diseases 3.Patients with serious systemic diseases, such as diabetes, cardiovascular diseases, etc. 4.Patients allergy to test drug or tool.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pregnancy-Unique Quantification of Emesis and Nausea,(PUQE) 14 days PUQE scale is divided into three dimensions, namely nausea, vomiting and retching.
- Secondary Outcome Measures
Name Time Method Mental state score 14 days Self-rating Anxiety Scale (SAS) score;Self-rating Depression Scale (SDS) score,Laboratory tests 14 days human chorionic gonadotropin (HCG);serum levels of vasoactive intestinal peptide (VIP), Motilin (MLT) and Gastrin (GAS)