study conducted to see the effect of Kanchanar guggulu and Amrutadi kwath in prostate enlargment.

Not yet recruiting

Conditions: Benign prostatic hyperplasia without lower urinary tract symptoms. Ayurveda Condition: MUTRAGHATAH,

Registration Number: CTRI/2022/08/044956

Lead Sponsor: BVVS Ayurved Medical College and Hospital

Brief Summary: *Mutraghata* is a disease of *Mutravaha Srothas* in which *Avarodha* i.e. obstruction to the flow of urine is the main feature. There are many conditions in *Mutravaha Srothas* where obstruction can be present, one such condition is *Vatashtila* explained under the heading of *Mutraghata* by Acharya Sushruta.1

In *Vatashtila, Prakupita Apana Vayu* located between *Shakrunmarg* and *Basti*, produces a glandular like swelling that causes *Mutrasanga*, *Atopa*, *Vithsanga*, *Mutraavrodha*, these features can be correlated with features of Benign Prostate Hyperplasia.2It is a nodular hyperplasia of prostate gland due to formation of one or more nodules, which leads to hesitancy, dysuria, frequency, urgency, haematuria, retention of urine.3

Benign Prostate Hyperplasia occurs in men over 50 years of age, by the age of 60 years 50 % of men have histological evidence of B.P.H. and 15 % have significant lower urinary tract symptoms, therefore there is an intense and persistent requirement to find a simple, safe and economical treatment for B.P.H.4

*Kanchanara Guggulu* is mentioned inSharangdhara Samhitain the management of *Granthi*5and *Amrutadi Kwatha* is explained in Bhaishajyaratnavali in the management of *Vatadi* *Mutrakricha*6.

In Yogratnakara, *Mutraghata Chikitsa Adhaya* in the context of *Samanya Kriya*, it is mentioned that *bheshaja* which are used in the management of *Ashamari* and *Mutrakricha* can be used in the *Mutraghata* *Chikista7*.

*Amrutadi Kwatha* ingredients having properties of *Medhohara* and *Vata Kaphahara, Mutral, Rasayana* in *Karma*, where *Kanchanara Gugguluâ€™s*ingredients having properties of *Vata Kapha Shamaka*, *Basti Shodhaka ,Granthighna* and *Mutral*.8

By taking the above references the study is undertaken to evaluate the combined effect of *Amrutadi Kwatha* and *Kanchanara Guggulu* in the management of *Mutraghata* with special reference to Benign Prostate Hyperplasia.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: Male

Target Recruitment: 30

Inclusion Criteria

The cases with features mentioned in International prostate symptoms scoring namely Frequency of urination Intermittency of urination Urgency Straining Weak stream of urine Nocturia Incomplete emptying of bladder Cases of BPH confirmed by USG within mild and moderate grade 30 â€“ 50 grams.

Exclusion Criteria

Ca Prostate and other metastatic and neoplastic conditions Neurological disease of urinary system, Stricture Urethra Patients with Infectious diseases like RVD, HBsAg. Exceeding more than 100ml volume with weight more than 100gm Patient having more than 10cm width x 8cm height x4cm thickness According to I-PPS chart 20-35 scoring is severe are exclude.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Effect of kanchanar guggulu in the management of mutraghata with special reference to BPH	21th day

Secondary Outcome Measures

Name	Time	Method
To compare the effect of Kanchanara Guggulu and Amrutadi Kwatha in the management of Mutraghata with special reference to BPH	21th days

Trial Locations

Locations (1): BVVS Ayurved Medical College and Hospital
🇮🇳
Bagalkot, KARNATAKA, India
BVVS Ayurved Medical College and Hospital
🇮🇳Bagalkot, KARNATAKA, India
Dr Ainapure Kiran Ravindra
Principal investigator
9172819633
kiranainapure76@gmail.com