Real-Time Support for Exercise Persistence in COPD

Phase 1

Completed

• Conditions: Pulmonary Disease, Chronic Obstructive; COPD; Emphysema; Chronic Bronchitis
• Interventions: Behavioral: Coached exercise persistence intervention; Behavioral: Self-Monitored exercise persistence intervention

• Registration Number: NCT00373932
• Lead Sponsor: University of Washington

Brief Summary

The purpose of this exploratory study is to determine the feasibility, acceptability, and efficacy of an exercise persistence intervention for patients with chronic obstructive pulmonary disease (COPD) following pulmonary rehabilitation (PR).

Detailed Description

Exercise, a cornerstone of PR, is effective in improving dyspnea, functioning, and health related quality of life (HRQL) in patients with COPD. However, these improvements gradually dissipate following program completion. There are currently few successful interventions that support patients' persistence with community-based exercise after PR and that have closely monitored the potentially negative impact that COPD exacerbations have on exercise behaviors. Emerging technologies such as wirelessly enabled personal digital assistants (PDA) may provide an innovative means to support exercise persistence through real-time collaborative monitoring of exercise and signs and symptoms of COPD exacerbations and reinforcement to enhance exercise self-efficacy. Patient graduates of two PR programs who have COPD (n=20) will first undergo a 2-week run-in prior to being randomized to either the MOBILE (Mobilizing Support for Long-term Exercise) intervention or attention control for 6 months.

Study Timeline

• Study Start: 2006-05
• Study First Submitted: 2006-09-06
• Study First Submitted QC: 2006-09-06
• Study First Posted: 2006-09-08
• Primary Completion: 2008-12
• Study Completion: 2008-12
• Status Verified: 2009-12
• Last Update Submitted: 2009-12-03
• Last Update Posted: 2009-12-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 17

Inclusion Criteria

• Moderate to severe COPD (FEV1/FVC <70% and FEV1%<80%)
• Ability to speak, read and write English
• Age 40 or older
• Willingness to complete a 6 month program

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Exclusion Criteria

• Illnesses such as bronchiectasis, active malignancies or other end stage diseases
• Plans to continue in a maintenance program after rehabilitation.

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
MOBILE-A	Coached exercise persistence intervention	Coached exercise persistence intervention
MOBILE-B	Self-Monitored exercise persistence intervention	Self-monitored exercise persistence intervention

Primary Outcome Measures

Name	Time	Method
Exercise behavior	3 & 6 Months

Secondary Outcome Measures

Name	Time	Method
Self-efficacy for exercise	3 & 6 Months
Perception of support	3 & 6 Months
COPD exacerbation	3 & 6 Months
Exercise Performance	3 & 6 months
Health related quality of life	3 & 6 months

Trial Locations

Locations (1)

University of Washington; 🇺🇸 Seattle, Washington, United States