Evaluation of Surface Characteristics and Antibacterial properties of Silver Nanoparticle doped Stainless Steel Bands – A Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 18
- 试验地点
- 1
- 主要终点
- antibacterial effect of silver nanoparticles
研究概览
简要总结
This randomized controlled trial evaluates the antibacterial efficacy and surface characteristics of silver nanoparticle coated orthodontic stainless steel bands The study addresses plaque accumulation and white spot lesions common during fixed orthodontic treatment Silver nanoparticles known for their antimicrobial properties are applied using physical vapor deposition Surface roughness and bacterial adhesion will be analyzed using SEM EDX and ImageJ software Eighteen participants are divided into coated and uncoated groups for comparison The aim is to determine if AgNP coatings can reduce bacterial colonization and improve clinical outcomes
研究设计
- 研究类型
- Interventional
- 分配方式
- Other
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 45.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients aged above 18 years No antibiotic and antibacterial mouthwash No history of smoking No history of systemic diseases.
排除标准
- •Patients with compromised immune status Pregnant women Patients with syndromes and craniofacial anomalies Patients with periodontal disease Patients allergic to silver.
结局指标
主要结局
antibacterial effect of silver nanoparticles
时间窗: after 1 and half year
次要结局
- surface smootehning after silver nanoparticle coating which will further decrease the antibacetrial adhesion(after 1 and half year)
研究者
Rachamadugu Jahnavi
MAnipal College of Dental Sciences