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Clinical Trials/NCT01750463
NCT01750463
Completed
Not Applicable

Verifying the Accuracy of the Masimo Pronto Non-Invasive Hemoglobin (Hb) Monitor and Associated Rainbow Probes Compared to Measured Laboratory Values in Critically Ill Pediatric Patients

University of North Carolina, Chapel Hill1 site in 1 country65 target enrollmentStarted: January 2013Last updated:

Overview

Phase
Not Applicable
Status
Completed
Enrollment
65
Locations
1
Primary Endpoint
Comparison of standard hemoglobin monitoring vs. the MASIO non-invasive hemoglobin monitor

Overview

Brief Summary

This is a prospective study to determine the accuracy of the Masimo Pronto Non-Invasive Hemoglobin Monitor and associated Rainbow® probes in the detection of hemoglobin concentration in critically ill children.

Detailed Description

This is a prospective study to determine the accuracy of the Masimo Pronto Non-Invasive Hemoglobin Monitor and associated Rainbow® probes in the detection of hemoglobin concentration in critically ill children. Data from at least 30 patients admitted to the Pediatric Intensive Care Unit (PICU) over a period of 2 months will be collected and analyzed for this study.

Note, that this device would not lead to deviations in routine patient care; specifically, the non-invasive monitor placed on the patient's finger is FDA approved. The proposed monitors are identical macroscopically to monitors, which are currently used to measure oxygen saturation at this institution. Clinical decisions, additional blood draws or alterations to the plan of care will not be made based on study data. The objective is to compare the validity of the hemoglobin values determined from non-invasive technology with measured laboratory values for hemoglobin utilized as standard of care.

Study Design

Study Type
Observational
Observational Model
Cohort
Time Perspective
Prospective

Eligibility Criteria

Ages
30 Days to 18 Years (Child, Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Patient has been admitted to Pediatric Intensive Care Unit
  • Patient age is ≥ 30 days old and ≤ 18 years old
  • Patient weight ≥ 3 Kg.
  • Patient requires hemoglobin monitoring

Exclusion Criteria

  • Patient does not have exposed fingers/toes,due to congenital anomalies wound dressing or injury.
  • Patient weight is less than 3 Kg
  • Patient is less than 30 days old

Outcomes

Primary Outcomes

Comparison of standard hemoglobin monitoring vs. the MASIO non-invasive hemoglobin monitor

Time Frame: up to 48 hours, post PICU admission

We will obtain measurements using the Masimo Pronto device prior to the standard lab draw at the following time points: post admission to PICU, 12-48 hours. We will then perform analysis using Bland Altman methods to determine the degree of agreement. Data analysis will occur 1 year after enrollment completion.

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Sean McLean, MD

MD

University of North Carolina, Chapel Hill

Study Sites (1)

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