Transmission Of Respiratory Tract microOrganisms In a School Environment

Recruiting

• Conditions: respiratory tract infections; 10004018

• Registration Number: NL-OMON56507
• Lead Sponsor: eids Universitair Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 9 September 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 78

Inclusion Criteria

Children between the age of 4 and 7 years old or adult teacher attending the
class

Exclusion Criteria

Insufficient proficiency of parents in Dutch or English language

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Primary study parameter<br /><br>To answer the primary objective we will record Spn carriage over time at a<br /><br>serotype level using qPCR. This will lead to a categorical variable with the<br /><br>following levels for each included serotype, per participant: never infected<br /><br>(no Spn detected during the sampling period), already colonized (Spn detected<br /><br>at the start of the sampling period), new colonization (Spn not detected at the<br /><br>start of the sampling period, but detected in the course of the sampling<br /><br>period) or re-colonization (same Spn serotype detected during sampling period<br /><br>with at least 3 samples in between not detecting Spn).<br /><br><br /><br>A transmission event will be defined as a SPn serotype that is observed in at<br /><br>least one child in the class and at a later timepoint also observed in one or<br /><br>more other children, as long as this is within 1 week of it being present in<br /><br>first child.</p><br>