Supermicrosurgical LVA for Lymphedema Treatment

Completed

• Conditions: Lymphedema
• Interventions: Other: LVEEA; Other: LVESA; Other: LVSEA

• Registration Number: NCT04285762
• Lead Sponsor: Chang Gung Memorial Hospital

Brief Summary

LVA orientations such as lymphaticovenous end-to-end (LVEEA), end-to-side (LVESA), and side-to-end (LVSEA) are commonly performed. Each orientation has its own advantages and disadvantages. The key factors affecting the type of anastomotic orientation are the sizes of the LVs and the RVs, and the relative distance between them. Most published literatures have focused on LVSEA2-9, which is considered to be the most efficient. With one anastomosis in LVSEA, the RV is able to drain both the antegrade and retrograde lymphatic flow. Nevertheless, how to determine the anastomotic orientation has remained ambiguous. In this study, we aimed to establish the basis of selecting the proper anastomotic orientation, based on the size and comparative size discrepancy between LV and RV. To the best of our knowledge, this is the first report to focus on this subject.

Detailed Description

Not available

Study Timeline

• Study Start: 2018-11-01
• Primary Completion: 2019-07-30
• Study Completion: 2019-12-31
• Status Verified: 2020-02
• Study First Submitted: 2020-02-24
• Study First Submitted QC: 2020-02-24
• Last Update Submitted: 2020-02-24
• Study First Posted: 2020-02-26
• Last Update Posted: 2020-02-26

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• lymphedematous lower limbs (International Society of Lymphology stage I-III) between March 2016 to October 2018 were included

Exclusion Criteria

• Patients whose data were missing will be excluded.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Patients underwent supermicrosurgical LVA	LVEEA	Patients underwent supermicrosurgical LVA by a single surgeon from March 2016 to October 2018.
Patients underwent supermicrosurgical LVA	LVESA	Patients underwent supermicrosurgical LVA by a single surgeon from March 2016 to October 2018.
Patients underwent supermicrosurgical LVA	LVSEA	Patients underwent supermicrosurgical LVA by a single surgeon from March 2016 to October 2018.

Primary Outcome Measures

Name	Time	Method
survival or failure	up to 3 months	The primary free flap outcome was determined as its survival or failure.

Trial Locations

Locations (1)

Kaohsiung Chang Gung Memorial Hospital; 🇨🇳 Kaohsiung, Taiwan