Inter-observer Variation in Gross Tumor Delineation of Esophageal Cancer on MR, CT and PET CT
- Conditions
- Esophageal Cancer
- Registration Number
- NCT05611658
- Lead Sponsor
- Institute of Oncology Ljubljana
- Brief Summary
The aim of the study is to investigate inter-observer variation in gross tumor volume (GTV) delineation of oesophageal cancer on different imaging modalities - CT, PET CT and MR.Twenty-three consecutive patients with esophageal cancer treated with preoperative or curative chemoradiotherapy were selected. All patients had CT, PET CT and MR imaging in treatment position prior to radiotherapy.Five experienced observers from our institution will independently delineate GTV on CT alone, MR alone, PET CT alone, on co-registered CT and MR and co-registered PET CT and MR. Inter-observer agreement, expressed in generalized conformity index (CIgen) and mean volumes of GTV will be calculated per patient and imaging modality.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 23
- locally advanced esophageal cancer eligible for treatment with preoperative or curative chemoradiotherapy
- contraindications for MR
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Change of interobserver variability in target volume delineation on CT, PET CT and MR. Through study completion, an average of 1 year. To compare target volume delineation of esophageal cancer using CT, PET CT and MR with determining generalized conformity indexes and mean volumes of GTV.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Institute of Oncology
🇸🇮Ljubljana, Slovenia