Effects of increased uric acid levels in pregnant patients
Not Applicable
Completed
- Conditions
- Health Condition 1: null- This study will be conducted in normotensive parturients undergoing non-elective cesarean delivery under subarachnoid block
- Registration Number
- CTRI/2015/04/005702
- Lead Sponsor
- PGIMER
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 100
Inclusion Criteria
this prospective observational study will be conducted in 100 women with singleton pregnancy and normal blood pressure admitted to the institute and coming for non-elective cesarean section
Exclusion Criteria
exclusion criteria will be:
-Pre-eclampsia or eclampsia
-Placenta praevia
-Previous cesarean delivery
-Pre-existing heart disease, liver or renal disorders
-Pre-existing or gestational diabetes mellitus
-Presence of coagulation abnormalities
-Presence of hyperuricaemia before pregnancy
-Twin pregnancy
-Patients undergoing cesarean delivery under general anaesthesia
-Patients demanding labor analgesia
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1 Incidence of post spinal hypotension as determined by total vasopressor used to keep systolic blood pressure more than 100 mmHg or to prevent a fall of more than 20% in MAP.Timepoint: Intraoperative period
- Secondary Outcome Measures
Name Time Method 2.Use of supplemental uterotonics required to maintain a tonus uterus. (Satisfactory(score more than 7) or unsatisfactory(score less than or equal to 7) as rated by the obstetrician using Duttaâ??s scoring system.) <br/ ><br>3.Estimation of blood loss measured as a fall in the pre and postpartum haematocrit of more than 30%. <br/ ><br>4.Short term neonatal outcome: Cord gases,1,5 minute Apgar scores, need for neonatal resuscitation. <br/ ><br>Timepoint: intraoperative and immediate postoperative period