跳至主要内容
临床试验/NCT04378374
NCT04378374已完成不适用

The Effect of Food Formulated With Pulse Flours on Blood Glucose, Satiety and Food Intake

Mount Saint Vincent University2 个研究点 分布在 1 个国家目标入组 54 人开始时间: 2019年9月16日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
54
试验地点
2
主要终点
Blood Glucose

研究概览

简要总结

Pulse flours represent a fast-growing segment on the functional food market; however, their health effects are not well understood. The observational studies and acute trials have established the link between frequent consumption of cooked whole pulses (beans, peas, lentils and chickpeas) and healthier body weight and improved blood glucose control. However, it is not clear whether these effects still remain after the processing of pulses into flours. The investigators hypothesized that the baked food products formulated with lentil flour of the same particle size as all-purpose wheat flour may reduce postprandial glycaemia and elicit a stronger suppression of subjective appetite due to its higher content of protein and resistant carbohydrate compared to all-purpose wheat flour. The treatments will be formulated either with lentil flour or with all-purpose wheat flour of similar particle size or with their combination. The objective of the project is to test the effect of foods formulated with lentil flour and/or wheat flour on blood glucose, short-term food intake and subjective appetite.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Basic Science
盲法
Double (Participant, Investigator)

盲法说明

The participants and investigators are blinded and could not distinguish the food formulated with different flours. The taste and flavour in all treatments were similar due to added flavourings.

入排标准

年龄范围
19 Years 至 35 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Healthy young male and female adults (19-35 y) with body mass index (BMI) of 20.0-24.9kg/m2

排除标准

  • Breakfast skippers
  • Smokers (including e-cigarettes) / cannabis consumers
  • Those with BMI < 18.5 and > 24.5 kg/m2
  • People with chronic diseases
  • People with impaired blood glucose control
  • People taking medication that may affect central and peripheral mechanisms of food intake regulation, blood glucose control, cognitive performance and sedative medication.
  • People with intellectual disabilities (excluded due to their inability to comprehend hedonic and visual analogue scales used in the study).
  • People with food allergies or gastrointestinal disorders (e.g., IBS and others).

结局指标

主要结局

Blood Glucose

时间窗: 0-120 minutes

The concentration of venous blood glucose before and after each treatment consumption

Subjective Appetite

时间窗: 0-120 minutes

The subjective assessment of appetite parameters including desire to eat, fullness, hunger and a prospective food consumption measured with 100 mm Visual Analogue Scales with two opposite statements at each end (e.g., for the hunger scale, 0 mm means not hungry at all, and 100 mm means very hungry).

Food Intake

时间窗: 120 minutes

The amount of energy (kcal) consumed ad libitum at the test meal (pizza lunch) two hours after each treatment consumption

次要结局

  • Physical Comfort(0-120 minutes)
  • Palatability of Food(5 minutes)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Bohdan Luhovyy

Associate Professor

Mount Saint Vincent University

研究点 (2)

Loading locations...

相似试验