Contemporary Modalities in Treatment of Heart Failure
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 4,000
- 试验地点
- 1
- 主要终点
- Number of participants with reported deaths from any cause
研究概览
简要总结
The Contemporary Modalities In Treatment of Heart Failure Registry (COMMIT-HF) is an observational study on an all-comer systolic heart failure population hospitalized in a highly specialized cardiovascular center. The aim of the study is to assess the clinical characteristics, treatment modalities and prognosis in this population.
详细描述
The Contemporary Modalities In Treatment of Heart Failure Registry (COMMIT-HF) is a single-center observational study that is underway in the 3rd Chair and Department of Cardiology of Silesian Center for Heart Diseases in Zabrze, Poland. Data collection is patient-based (not event-based).
The main objective of the COMMIT-HF Registry is to clarify the overall clinical characteristics of systolic heart failure patients, their demographics and clinical profile, current management, in-hospital outcomes and long-term follow-up, with regard to the administered treatment.
The study population is formed by all-comer patients hospitalized in cardiology wards and intensive cardiac care units with a diagnosis of systolic heart failure. For the purpose of this study heart failure is defined as a set of symptoms resulting from myocardial systolic function impairment, confirmed in resting transthoracic echocardiography with left ventricular ejection fraction (LVEF) ≤35%. Patients with acute coronary syndromes are excluded from the analysis.
Complete patient demographics; medical history, complete hospitalization data (diagnostic and therapeutic) and in-hospital results are collected in an electronic form by the attending physician. The patients are under constant follow-up for all cause mortality and major adverse events.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •symptom based diagnosis of heart failure
- •echocardiographically confirmed impaired left ventricular ejection fraction ≤35%.
排除标准
- •acute coronary syndrome on admission
- •≥ 18 years old
结局指标
主要结局
Number of participants with reported deaths from any cause
时间窗: From date of inclusion until the date of death from any cause, assessed up to 1 year
次要结局
- Number of participants with reported cerebrovascular insult(From date of inclusion until the date of first event, assessed up to 1 year)
- Number of participants with reported heart-failure related rehospitalization(From date of inclusion until the date of first event, assessed up to 1 year)
- Number of participants to undergo orthotopic heart transplantation(From date of inclusion until the date transplantation, assessed up to 1 year)
- Number of participants with reported myocardial infarction(From date of inclusion until the date of first event, assessed up to 1 year)
- Number of participants to undergo mechanical circulatory support implantation(From date of inclusion until the date implantation, assessed up to 1 year)
研究者
Mariusz Gasior
Professor, PhD
Silesian Centre for Heart Diseases