Comparison of salivary IL-1 beta in moderate to severe chronic generalized periodontitis among healthy subjects and patients with type 2 diabetes
Not Applicable
- Conditions
- Diabetes Mellitus.Non-insulin-dependent diabetes mellitus
- Registration Number
- IRCT2014110916246N2
- Lead Sponsor
- Research Vice-chancellor
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 56
Inclusion Criteria
having the history of type 2 diabetes or people who have more than 2 consecutive blood glucose levels more than 126 mg / dl; the average age of 40-60 years old; having chronic generalized periodontitis that have more than 30% attachment lose; willing to participate in the study. Exclusion criteria: unwillingness to participate in the study; any systemic disease other than diabetes and debilitating diseases that can effect on oral health person's; any non-surgical periodontal therapy that has been done over the last 9 months; smoking or quit smoking less than 5 years; pregnancy or intend to become pregnant during the study period of 6 month.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method IL-1beta. Timepoint: Before intervention. Method of measurement: ELISA.
- Secondary Outcome Measures
Name Time Method Generalized chronic periodontitis and chronic periodontitis with diabetes and without diabetes. Timepoint: Before intervention. Method of measurement: PD,CAL, BOP PI, FBS, HbA1c.